The universe of Inborn Errors of Immunity is expanding at a fast pace. Currently, there are more than 550 Inborn errors of Immunity and more than 500 disease causing genes. There have been recent advances in human immunology and in IEI. However, there are challenges in IEI ranging from interpretations of genetic variants to global access to care for IEI and challenges in HSCT and availability of gene therapy and gene editing for IEI.  Furthermore, there are major developments in our understanding of the role of intrinsic and innate immunity in defense against microbes, especially viruses. Novel inborn errors of innate and intrinsic immunity have been discovered, which is the theme of the 20^th International symposium.  Leading experts from all over the globe will be discussing these areas at the 20^th International Symposium on IEI to be held on the -1^st November 2025 at VEA Newport Beach, Newport Beach, California.

We invite you and your colleagues, fellows, and students to attend.  Space is limited to 100 participants. Therefore, early registration is encouraged. Deadline for registration is September 1

A small number of abstracts will be accepted for oral presentation.

Sincerely,

Jean-Laurent Casanova, Sudhir Gupta, Luigi Notarangelo

Organizers

Join us for our annual Patient Education Day to improve knowledge about Primary Immunodeficiency Diseases.

With 10 to 12 new primary immunodeficiency diseases (PIDs) discovered each year, the landscape of understanding these conditions is ever-changing. Currently, there are 557 known PIDs—also referred to as Inborn Errors of Immunity—and over 413 associated disease-causing genes. Every year, exciting new insights into their clinical presentations, complications, and treatment options emerge.

Our expert speakers will dive deep into the workings of the immune system, highlight the clinical features and complications of various primary immunodeficiencies, and explore treatment options such as immunoglobulin therapy, hematopoietic stem cell transplantation, and cutting-edge gene therapies. With more than two hours dedicated to Q&A, you’ll have ample opportunity to engage and get your questions answered by top professionals in the field.

ADMISSION IS COMPLIMENTARY

Join us for our annual Physicians Education Day to improve knowledge about Primary Immunodeficiency Diseases.

Speakers provide information about working of the immune system, clinical features and complications of primary immunodeficiency diseases, and various treatment options including immunoglobulin, hematopoietic stem cell transplantation, and gene therapy.

ORGANIZED BY: Foundation for Primary Immunodeficiency Diseases

ADMISSION IS COMPLIMENTARY

Use the BOOK TICKET button above and follow the CHECKOUT INSTRUCTIONS.

Contact: Michelle Tran Phone: (949) 824-8334; FAX: (949) 824-4362, e-mail thumt@hs.uci.edu

Registration can also be made with this form and sent my email.

Valet parking, Breakfast, and lunch are hosted