20th International Symposium on Inborn Error of Immunity: Innate and Intrinsic Immunity

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Description

The universe of Inborn Errors of Immunity is expanding at a fast pace. Currently, there are more than 550 Inborn errors of Immunity and more than 500 disease causing genes. There have been recent advances in human immunology and in IEI. However, there are challenges in IEI ranging from interpretations of genetic variants to global access to care for IEI and challenges in HSCT and availability of gene therapy and gene editing for IEI.  Furthermore, there are major developments in our understanding of the role of intrinsic and innate immunity in defense against microbes, especially viruses. Novel inborn errors of innate and intrinsic immunity have been discovered, which is the theme of the 20th International symposium.  Leading experts from all over the globe will be discussing these areas at the 20th International Symposium on IEI to be held on the -1st November 2025 at VEA Newport Beach, Newport Beach, California.

We invite you and your colleagues, fellows, and students to attend.  Space is limited to 100 participants. Therefore, early registration is encouraged. Deadline for registration is September 1

A small number of abstracts will be accepted for oral presentation.

Sincerely,

Jean-Laurent Casanova, Sudhir Gupta, Luigi Notarangelo

Organizers

Abstract

A limited number of abstracts will be selected for oral presentation.  There is no poster presentation. Abstract may be prepared on a single page (8×11) types in single space. It should include title in bold, name of authors (presenting author in bold), and name of the institute. Abstract must be formatted under Rationale, Methods, Results, Conclusions, and no references.  Deadline for abstract submission is October 1, 2024. 

Abstract may be submitted to sgupta@uci.edu

Scientific Program

 

October 31

Time Event
7:00 Am Registration
7:00 Am – 9:00 Am Breakfast (Riveira Lawn)
Session I (Co-Chairs: Dan Kastner & Trine Mogensen)
9:00 Am – 9:10 Am Sudhir Gupta – Welcome And Introduction
9:10 Am – 9:50 Am Andras Spaan – Inborn Errors Of Cell-Intrinsic Immunity: Lessons Learned From Staph Aureus
9:50 Am – 10:30 Am Jean-Laurent Casanova – Human Inborn Errors Of Intrinsic Immunity
10:30 Am – 10:50 Am Coffee Break
10:50 Am – 11:30 Am Zhijian Chen – Roles Of Cgas-Sting Signaling In Inflammation And Autophagy
11:30 Am – 12:10 Pm John Macmicking – New Players In Ifn-Induced Cell-Intrinsic Immunity To Infection
12:10 Pm – 12:50 Pm Nan Yan – Sting Signaling In Inborn Error Diseases
12:50 Pm – 2:00 Pm Lunch (Riviera Lawn)
Session Ii (Co-Chairs: Luigi Notarangelo & John Macmicking)
2:00 Pm – 2:50 Pm Virgina Pasqual – Thomas Waldmann Award Lecture: Systemic Lupus Erythematosus: Interferon And Beyond
2:50 Pm – 3:30 Pm Mark Anderson – Control Of Immune Tolerance By Thymic Epithelium
3:30 Pm – 3:50 Pm Coffee Break (Reviera Lawn)
3:50 Pm – 4:30 Pm Helen Su – New Insights Into Mechanisms Of Human Immunity From Studying A Novel Inborn Error Of Immunity
4:30 Pm – 4:50 Pm Rajni Kumarh (Abstract) – Trogocytosis Between Dendritic Cells, T Follicular Helper And B Cells
4:50 Pm – 5:30 Pm Oral Abstracts (2)
5:30 Pm Adjourn
6:30 Pm Speakers Dinner (Capri Room)

November 1

Time Event
7:00 Am Registration
7:00 Am – 9:00 Am Breakfast (Riveira Lawn)
Session Iii (Co-Chairs: Sudhir Gupta & Zhijian Chen)
8:30 Am – 9:20 Am Rafi Ahmed – William E Paul Award Lecture: What Is T Cell Exhaustion?
9:20 Am – 10:00 Am Daniel Kastner – The Notch4 Dossier: Inborn Errors Of Angiogenesis
10:00 Am – 10:40 Am Dusan Bogunovic – Innate Immune Memory Of Inflammation
10:40 Am – 11:00 Am Coffee Break
11:00 Am – 11:40 Am Christina Kozycki – Dissecting Tissue Specific Innate Immune Signaling: Lessons From Alpk1-Related Autoinflammatory Disease
11:40 Am – 12:20 Pm Ivona Aksentijevich – Novel Insights In The Pathogenesis Of Autoinflammation: Contribution Of Cell Death Pathways
12:20 Pm – 1:30 Pm Lunch
Session Iv (Co-Chairs: Jean-Laurent Casanova & Dusan Bogunovic)
1:30 Pm – 2:10 Pm Megan Cooper – Novel Mechanisms Of Genetic Errors Of Immunity
2:10 Pm – 2:40 Pm Andras Spaan – Inborn Errors Of Cell-Intrinsic Immunity: Lesson Learned From Staph Aureus
2:40 Pm – 3:20 Pm Sharon Morley – Novel Coenzyme Q6 Variant Increases Susceptibility To Pneumococcal Disease
3:20 Pm – 3:40 Pm Coffee Break
3:40 Pm – 4:20 Pm Trine Mogensen – Inborn Errors Of Immunity In Patients With Viral Infections In The Cns
4:20 Pm – 5:00 Pm Shen-Ying Zhang – Genetic Defects Of Brain Immunity In Childhood Viral Encephalitis
5:00 Pm Adjourn
6:00 Pm – 10:30 Pm Gala Banquet And Entertainment (Invited Speakers And Tickets)
6:00 Pm – 7:00 Pm Cocktail Reception (Riviera Lawn)
7:00 Pm – 10:30 Pm Dinner And Entertainment (Riviera Ballroom)

Accomodations

For your convenience, a block of rooms has been reserved.  Please use the link below or call to make your  reservation.

Guests can reserve their rooms https://book.passkey.com/e/50814951 or (877)622-3056 to speak directly to reservations. When calling to make your reservation, please mention the FPID Symposium & Gala in order to receive a discounted rate.

VEA Newport Beach
900 Newport Center Dr
Newport Beach, CA 92660, USA

Gala Fundraiser

Nov 1, 2025

Theme: 1920 Great Gasby

Featuring: Legendary Entertainer Joe Piscoppo

Click here for more details

Event Details

Start date: October 31, 2025

End date: November 1, 2025

Start time: 07:00 a.m. PDT

End time: 05:00 p.m. PDT

Venue: VEA Newport Beach, Newport Beach, California, USA